Summary
Iron deficiency is very common worldwide, and unfortunately, it affects premenopausal women to a large extent. Fortunately, iron deficiency can easily be counteracted with iron supplements. However, synthetic isolated iron is not absorbed as well and, more importantly, can lead to severe gastrointestinal issues. A clinical study shows that whole food iron restores iron levels without gastrointestinal problems.
A clinical study shows that the whole food iron supplement Iron Response restores iron levels within eight weeks without the gastrointestinal issues commonly associated with iron supplements.
Iron deficiency is very common worldwide. Patients with non-anaemic iron deficiency have normal haemoglobin levels (Hgb ≥ 12 g/dl) but low serum ferritin levels (SF <20 μg/l). Around 8–16% of premenopausal women are affected by non-anaemic iron deficiency. Premenopause typically begins between the ages of 40 and 45 and lasts for approximately 3–5 years. During premenopause, ovulations become less regular than before.
A clinical study was conducted to determine whether a low-dose iron supplement such as MegaFood Blood Builder (the exact same supplement as Innate Response Iron Response, produced by the same manufacturer) could increase iron levels without causing the common negative side effects typically associated with iron supplements. In fact, 50% of patients treated for iron deficiency discontinue their treatment prematurely due to gastrointestinal discomfort caused by synthetic isolated iron. Supplements containing isolated synthetic iron are not absorbed as well as those that include the natural cofactors of iron. One example of an iron cofactor is ascorbic acid (vitamin C), which helps maintain iron in its bioactive reduced form (Fe2+), thereby increasing absorption. Innate Response Iron Response contains vitamin C, which enhances the bioavailability of iron, along with other factors to optimise blood health.
In the clinical study, which lasted eight weeks, premenopausal women with non-anaemic iron deficiency were given MegaFood Blood Builder/Innate Response Iron Response. Data was also collected on constipation, nausea, vomiting, and diarrhoea, which are common side effects of high doses of synthetic isolated iron. After eight weeks of taking MegaFood Blood Builder/Innate Response Iron Response, haemoglobin levels increased from 12.8 g/dl to 13.2 g/dl, serum ferritin levels from 13.9 μg/l to 21.1 μg/l, and total body iron stores from 6.77 mg/kg to 8.57 mg/kg. Fatigue index decreased from 2.8 to 1.8, and there were no signs of gastrointestinal side effects typically associated with iron supplements. The study demonstrates that Iron Response increases haemoglobin and iron levels even at a lower dose than many synthetic isolated iron supplements, while avoiding the common side effects associated with iron supplementation.
Author
Scientific references and sources
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